Raman spectroscopy, as a label-free, nondestructive fingerprint detection technique, has been widely used in various application fields, including trace-molecule detection, biomolecular analysis, chemical analysis, material characterization, bioassay, and archeological and criminological identification. However, normal Raman signals are too low to be detected, which limits the application of Raman spectroscopy in many fields.
Sixty years ago, the first laser was successfully fired on May 16, 1960 by Dr. Theodore Maiman. Seven weeks later, Dr. Maiman and his employer, Hughes Aircraft Company, presented laser to the world at a press conference in Manhattan.